Genetron® Refrigerants

Genetron AZ-20 (R-410A)

Genetron 123

Get the AZ-20 story at www.410a.com!

Genetron AZ-20 is the original brand of R-410A refrigerant, invented by Honeywell as the primary global solution to replace ozone-depleting refrigerants in residential and commercial unitary air conditioners. R-410A is an azeotropic mixture of HFC-32 and HFC-125, with near-zero glide allowing for both predictable performance and easy handling and recycling. Millions of R-410A air conditioners have been sold around the world, and over 25 equipment manufacturers now offer an R-410A option in their product line.


R-410A has a significantly higher capacity and moderately higher operating pressure than R-22, making it a cost-effective replacement for R-22 in higher-efficiency air conditioning and heat pump systems. In new unitary systems optimized for R-410A use with either scroll or reciprocating compressors, R-410A has been shown in tests to have a 5-to-6 percent higher Energy Efficiency Rating (EER) than R-22. The higher capacity also enables the design of smaller, more compact air-conditioning equipment.


Because it behaves like an azeotrope, R-410A is easy to service in the field. It won't meaningfully change composition if an air conditioner suffers a refrigerant leak, and R-410A can be easily recovered and reclaimed, giving it a substantial advantage over other R-22 replacements such as R-407C or R-417A. R-410A has been given an A1 safety classification by ASHRAE.


R-410A is not designed for use as a retrofit refrigerant for R-22. Working with R-410A requires that you use tools, pumps, and recovery equipment and tanks rated for the higher pressure.


Genetron AZ-20 refrigerant is available in a variety of package sizes. Equipment manufacturers who require help in converting their products from R-22 to R-410A should contact us to take advantage of our global experience in helping OEMs to optimize systems for this high-performance refrigerant.